منابع مشابه
Local immunomodulation for cancer therapy
In murine models of cancer, we have achieved efficient systemic activation of tumor-specific T cells by the local administration of a CTLA4-blocking antibody at low doses. Using a slow-release formulation, we could drastically lower the serum levels of the antibody, hence decreasing adverse effects and the risk of autoimmune reactions, without losing systemic efficacy.
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ژورنال
عنوان ژورنال: Journal of Gastrointestinal Oncology
سال: 2018
ISSN: 2078-6891,2219-679X
DOI: 10.21037/jgo.2017.06.08